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Indeed, previous studies involving prenatal exposure to As in rats demonstrated decreased BDNF expression and social isolation-like behavior (Mimouna et al., 2018)

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While BVZ is well tolerated, suppression of VEGF activity often results in some common toxicities, such as hypertension, gastrointestinal perforation, thromboembolic events, cerebral haemorrhage, problems with wound healing, and proteinuria etc