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37,6669 Its main drawback is that it is applicable only in patients with encephalopathy, and when patients reach this stage, their condition often deteriorates rapidly, and they die while awaiting liver transplant

This stability is essential as it prevents the premature release of the drug before it reaches the targeted cells

AFP1 results from o-demethylation while the AFB1 epoxide is formed by epoxidation at the 2,3 double bond Aflatoxicol is the only metabolite of AFB1 produced by a soluble cytoplasmic reductase enzyme system [46]

Its metabolism proceeds via a complicated enzymatic pathway, acting both as detoxification and producing more toxic intermediates