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Excessive DSIP dosing typically causes headaches, grogginess, or paradoxical insomnia rather than dangerous effects

In addition, iodine supplementation in iodine-deficient areas has been associated with an increased risk of thyrotoxicosis, supporting the U-shaped relationship between iodine status and thyroid disorders [17, 18]

Nevertheless, these discussions in no way include the multifactorial nature of the disease processes encompassing IBD, and intentionally have not included potential implications of genetic predispositions, spontaneous immune deregulations, proteases, and microbiota, which are discussed in great detail in other great review articles

Although the mechanisms underlying these three types of hepatotoxicity are not identical, they are not absolutely either/or, completely disconnected