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In the lungs, the reverse reaction occurs, allowing CO to be exhaled and oxygen to bind hemoglobin for delivery to tissues (60)

Addition of exogenous LPS caused an increase in SPARC, which in turn led to a decrease in the expression of ZO-1 and occluding, and finally a rise in BBB permeability at 24 h in a concentration-dependent manner ( Figure 1 )

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Therefore, the obtained nanosystem facilitated the simultaneous, controlled release of SA and bioavailable silicon, further enhancing callose deposition and reinforcing the defense of rice against plant pathogens [80, 81]