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She was subsequently appointed professor of pediatrics in laboratory medicine and pathobiology, and of medicine at the University of Toronto, and director of cardiovascular research at the Research Institute, Hospital for Sick Children, from 1988 until her recruitment to Stanford in 2002

Essential strategies to manage oxidative stress include: Reduce Toxic Burden : Environmental exposure to toxins, heavy metals, pollutants, and industrial chemicals can trigger oxidative stress by catalyzing ROS production, promoting free radical production, depleting antioxidants, and inhibiting their protective functions

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