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Discovery of ecnoglutide - A novel, long-acting, cAMP-biased glucagon-like peptide-1 (GLP-1) analog

Albiston AL, Diwakarla S, Fernando RN, Mountford SJ, Yeatman HR, Morgan B, et al

79 WooS

The ER also communicates with mitochondria via signaling from the unfolded protein response (UPR), which is activated by ER stress and signals through the three ER-resident stress sensors IRE1, PERK, and ATF6 (Walter and Ron, 2011)