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furthermore, JQ1 treatment or BRD4 knockdown results in downregulation of SLC7A11 as well as other ferroptosis regulators (Sui et al., 2019), suggesting that BRD4 might activate SLC7A11 transcription via epigenetic mechanisms, whereas JQ1-mediated BRD4 inhibition represses SLC7A11 expression and promotes ferroptosis

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