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Vascular disease and mechanism of endothelial dysfunction Elevated levels of Hcy are involved in the development and progression of vascular disease

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N -Acetyl-1,2- S -(1,2-dichlorovinyl)-L-cysteine sulfoxide reactivity is greater than that of other mercapturate sulfoxides, including those of N -acetyl-2,2- S -(1,2-dichlorovinyl)-L-cysteine, S -(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, and N -acetyl- S -(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine, which react only slowly or require bioactivation by glutathione S -transferase for conjugate formation (Ripp et al

Morbidity and Mortality Weekly Report