What makes MOTS-c unusual among peptides is its origin: rather than being encoded by nuclear DNA (the DNA in the cell nucleus), it is encoded by the mitochondrial genome the small, separate set of DNA found inside mitochondria, the energy-producing compartments of cells
The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication
Recommended Timing Protocols Morning Fasted Protocol (Most Common): Timing: Upon waking, before any food or caloric beverages Fasting Window: At least 8-10 hours fasted from overnight sleep Post-Injection: Wait 30-60 minutes before eating breakfast Activity: Light fasted cardio or morning routine before first meal may enhance fat mobilization Advantages: Convenient, consistent daily routine, maximizes overnight fasted state Pre-Exercise Protocol: Timing: 30-45 minutes before fasted cardio or training session Fasting Window: At least 4-6 hours since last meal Rationale: Exercise during fasted state with elevated free fatty acids may enhance fat oxidation Considerations: Not suitable for high-intensity training

It uses Kaneka brand ubiquinol, which is also used by more affordable products such as: Doctors Best Ubiquinol (Kaneka) 100 mg Nutricost Ubiquinol (Kaneka) 100 mg Inositol Rhonda first mentioned taking inositol in her Jan 2024 Q&A (#55) taking around 1 scoop (2 grams) of inositol before bed to improve her sleep quality