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Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis

Inhibiting LRRK2 activated this pathway, attenuated ferroptosis, reduced neuroinflammation, and improved motor deficits (Liu et al., 2025)

However, this method has also a disadvantage such as high production costs of (R)-4-chloro-3-hydroxybutyrate derivate, and a difficulty of application thereof to industrial-scale production in that the reaction must be carried out under high- temperature and high-pressure conditions

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