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Sinonasal melanoma arising from conjunctival primary acquired melanosis

Recently, a unique subpopulation of MSCs endowed with NCSC-like properties has been isolated from various adult NC-derived tissues, such as dental pulp [15, 57], oral mucosa/gingiva [16,17,18, 35, 36], and skin epidermis [19, 58]

This results in the accumulation of apoptotic cells, triggering secondary necrosis and further lung damage

Moreover, loss of hepatic PSAT1 impaired glucose tolerance in mice fed the SAAR diet and abolished the increase in liver serine sourced from circulating glucose without completely preventing the rise in liver serine levels