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Epidemiology (2017) 28(1):3042

Exposure to pristane causes lupus-like disease that is characterized by interferon(IFN)-I-dependent autoantibody production, inflammatory cytokines and renal diseases in susceptible mouse models ( Induction of pristane-induced autoantibodies has been shown to be dependent on the inflammatory cytokines as protective effects on nephritis and autoantibodies were observed in INF- / , IL-6 / , IL-12 / , and IL-17 / mice ( Silica Among the environmental and occupational agents associated with immune dysregulation, silica is considered a notable risk factor due to its widespread exposure

The compositions of table 3 reduced glutathion and sodium carbonate or sodium bicarbonate (calling product of the present invention in the following text) and existing freeze drying technology product draw moist test In sum, the freeze drying technology product (being reduced glutathion sodium) that gone on the market more of product of the present invention Have following characteristics: One of advantage long-time stability and dissolving rear stability all have clear superiority

pneumoniae have evolved sophisticated strategies that manipulate macrophage defense mechanisms in their favor, enabling survival and replication within the host