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There is, however, a synthetic analog of TH4 called TB-500, which has been investigated as a treatment for neurodegenerative conditions like multiple sclerosis, but its use is still largely experimental [4]

Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications

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[52] GPCRs respond to extracellular signals mediated by a huge diversity of agonists, ranging from proteins to biogenic amines to protons, but all transduce this signal via a mechanism of G-protein coupling