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Clinical investigations of SS-31 have produced encouraging findings in some indications while yielding mixed or negative results in others

housing, detox, addiction medicine clinic, family doctor services, safe injection facilities) Discuss and offer naloxone kits, clean injection supplies Counsel around high risk of accidental overdose given withdrawal and/or decrease in tolerance Pitfall: Sending an opioid patient directly to a detoxification center who is not psychologically ready to quit opioids can have devastating consequences

However, coffee enemas can result in electrolyte imbalance, infections, inflammation of the rectum and colon, and burns

Unlike buprenorphine (a partial agonist), it doesnt require waiting for withdrawal symptoms and shows fewer adverse effects like hypotension and sedation compared to 2 agonists