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after an intramuscular injection of 1,000 g of cyanoB 12 , about 150 g is ultimately retained in the body 15 Most vitamin B 12 -deficient individuals in the UK and other countries are treated with intramuscular vitamin B 12 , and vitamin B 12 replacement has been traditionally administered intramuscularly

However, most users report similar or better muscle gains when properly managing their nutrition, likely due to improved nutrient partitioning and insulin sensitivity

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Hypercobalaminemia, a phenomenon where the vitamin B12 levels in an individuals body are elevated, can occur due to various underlying factors such as: Liver disease Kidney disease Leukemia Myeloproliferative disorders What Medical Conditions Can Cause Low Vitamin B12 Levels