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Three key pathways contribute to ferroptosis (Figure 2): the amino acid metabolism pathway , where inhibition of cystine/glutamate exchange transporter System Xc-leads to reduced glutathione and inactivation of GPX4, an enzyme critical for lipid peroxide detoxification

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3,4,5-tri- O -caffeoylquinic acid 3,4,5-tri- O -caffeoylquinic acid, a caffeoylquinic acid derivative, ameliorates the learning and memory deficits in ageing mouse models[192]

Agod, et al