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Unlike GSTM1 and GSTT1 , however, where common polymorphisms result in complete gene deletions (Board, 1981), variant GSTP1 alleles differ from the consensus reference sequence by single amino-acid substitutions, resulting in less pronounced, less frequent and less well-characterised phenotypes (Peklak-Scott et al, 2008)

This allows the body to safely clear toxic homocysteine while maintaining a continuous, sustainable supply of cysteine for ongoing antioxidant defense

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Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina