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Description

Subsequently, an orange precipitate was formed that collected by filtration

S.TianZ.ZhangN.HanJ.GuoH

In genetic alterations, mutations of the SNCA gene [19], disruption of calcium homeostasis [20], impaired autophagy [21], oxidative stress, and other pathological conditions, the fibrillation process of -syn starts with the formation of dimers from misfolded monomers, which further develop into small oligomeric substances stabilized by -sheet-like interactions