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The miss regulation of the GSH levels caused a disruption of the redox homeostasis and the antioxidation defense system, yielding the accumulation of ROS and lipid peroxides

BioMed Res Int (2014) 2014:581256

Some organic nanomaterials, although generally low in toxicity, lack the mechanical strength to withstand the in vivo environment and show poor drug-loading capacity due to their structural and physicochemical limitations (Yu et al., 2023)