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Strictly speaking, DNA methylation in common research refers to the process in which the methyl group of SAM is transferred to the C-5 position of cytosine in the 5-CpG-3 dinucleotides (CpGs) under the function of DNMTs to form 5-methyl cytosine (Figure 1A)

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[ 194 ] The expression of peroxisome proliferatoractivated receptor (PPAR) and PPARdependent adipocyte differentiation is suppressed by BACH1 in primary mouse embryonic fibroblasts, suggesting that BACH1 is an inhibitory regulator of adipocyte differentiation and adipogenesis