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Discussion Challenges in establishing causal relationships between COVID-19 and PD Many concerns still need to be addressed, despite the fact that numerous linked research about COVID-19 and PD are beginning to emerge

Modulation of the immunosuppressive tumor microenvironment The BM niche in MM patients is intrinsically immunosuppressive, containing cells able to blunt the immune response and adenosine (ADO) that may lead to an anergic status of T, NK, and dendritic cells [10]

Accumulating evidence suggests that stress can activate an inflammatory response in the brain that may contribute to the risk of mental illness, depression, and other stress-related diseases (6, 7)

Can be used to treat anemia, nerve damage and cognitive decline