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Adipocytes and bone marrow stromal cells in the TME can promote the resistance of tumor cells to ASNase treatment by supplying Gln and cysteine to leukemia cells, 348,349 and cancer-associated fibroblasts can secrete Asp to promote solid tumor growth

Rao AD, Sugar EA, Chang DT, Goodman KA, Hacker-Prietz A, Rosati LM, Columbo L, O'Reilly E, Fisher GA, Zheng L, Pai JS, Griffith ME, Laheru DA, Iacobuzio-Donahue CA, Wolfgang CL, Koong AC , Herman JM

The relatively low radical reactivity of fluorescein may lead to underestimation of potent antioxidants with rapid reaction kinetics

Autophagic deficits in PD are also found in immune cells, which is particularly relevant because microglia are the predominant cell type responsible for clearing aggregated -synuclein in the CNS [142]