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Although only 5 10% of breast cancer is inherited, developments in molecular oncology and genetic screening technologies are allowing us to understand the role of genetic risk and develop personalized preventive and therapeutic plans for individual patients harboring pathogenic mutations (71)

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ALS is characterized by neurodegeneration of motor neurons in brain, spinal cord, and periphery, leading to progressive muscle paralysis: terminal events often comprise aspiration pneumonia and respiratory insufficiency (Morgan and Orrell, 2016