human glutathione synthetase enzymes Inborn errors in the metabolism of | Orphanet Journal of Rare Diseases Glutathione synthetase deficiency | MedLink

However, factors such as stress, poor diet, and exposure to toxins can deplete our bodys supply of glutathione, leading to a host of health issues

Loss of farnesoid X receptor (FXR) exacerbated the ferroptosis signaling pathway by enhancing iron accumulation, increasing lipid peroxidation, decreasing GSH levels and reducing GPX4 expression in cisplatin-treated mice and HK-2 cells [175]

The increase in ROS level due to inhibition or depletion of GSTP is common to normal and cancer cells

Am J Pathol 56:111 Meyers LD, Hellwig JP, Otten JJ (2006) Dietary reference intakes: the essential guide to nutrient requirements