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Li et al., 2007)

At week 15, rats were sacrificed to assess liver/body weight ratio, degree of liver fibrosis (Masons trichromic) and steatosis (oil red), and plasma endotoxin, IL1- and TGF- levels (ELISA) Results: All NASH rats increased in body weight, whereas liver/body weight ratio normalized in group 2

Cleavage by GSDMB leads to pyroptosis

Through the employment of microneedle technology, hepatic stellate cells within the liver are effectively inactivated, and the excessive degradation of the ECM is significantly facilitated (Fig