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Additionally, CD36 facilitates the uptake of fatty acids, exacerbates intracellular lipid peroxidation, and pushes T cells toward ferroptosis, which is marked by reduced production of essential cytotoxic cytokines

26 The hydrophobic domain of peptide assemblies can encapsulate hydrophobic drugs (eg, the chemotherapeutic agent paclitaxel) and enhance drug loading capacity through covalent coupling strategies

Adapter proteins are used to transfer the signal - in the case of insulin IRS-1 (insulin receptor substrate)

A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects