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Second, S-nitrosylation of Heat Shock Cognate 70 kDa protein (HSC70) at a critical cysteine in its ATP-binding domain enables the co-chaperone Csp to enhance F508del-CFTR folding and stability (Zaman et al., 2006)

Improperly stored Lipo B is unlikely to cause harm the primary risk is complete loss of therapeutic effect, not toxicity

Many therapies are administered as a "bolus" or one-time dose, but they may also be administered as an extended infusion or drip