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3D) (37,71,78,79,82,112,142)

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In contrast, the present review adopts a cytokine-centric mechanistic framework, organizing nutraceutical evidence according to their effects on defined inflammatory signaling axes, including NF-B activation, NLRP3 inflammasome signaling, TGF-/SMADmediated fibrogenesis, JAK/STAT pathways, macrophage polarization dynamics, and ferroptosis-associated inflammatory responses across hepatocytes, Kupffer cells, and HSCs