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These genetic manipulations could confer a GSH content of 12 % on the engineered strains

If, for example, this deficit is secondary to other primary pathologies that have already been diagnosed and require significant pharmacological treatments, the administration is done directly into the vein to obtain absolute and immediate effectiveness

Indeed, these behavioral improvements are clear indicators of gut microbiota modulation in which Akkermansia may increase along with beneficial SCFAs such as acetate and propionate, and the decrease of isobutyrate and stable n-butyrate levels in the gut

Leukemia 18(9):15181521