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As expected, the loss of membrane integrity in wild-type HeLa cells upon treatment with RSL3 or CHP was mostly prevented by liproxstatin-1 (Extended Data Fig

Phenolic compounds reduce the phosphomolybdate complexes present in the Folin-Ciocalteu reagent, forming a blue chromophore with maximum absorbance at 765 nm

All participants who provide both baseline and end of treatment blood samples will be included in a secondary dose-response analysis to account for potential early study withdrawals or poor compliance