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No probable etiologic factors were reported in any of the medical histories or additional examinations done at the clinic to which the patient was referred

For patients diagnosed with a significant vitamin B12 deficiency, our healthcare team typically begins treatment with more frequent injections, often weekly or even more often, until healthy vitamin B12 levels are restored

Furthermore, SAM is a precursor in the synthesis of melatonin and is also an enzymatic cofactor of glutathione production [29]

The vitamin B 12 supplementation study in pregnancy from South India 24 and the study from Bangladesh 26 used very high doses of 20100 RDA with no reported adverse effects