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Decreased cystine absorption and increased expression levels of ferroptosis-inhibiting molecules, such as SLC7A11 and GPX4, inhibited the occurrence of ferroptosis in TNBC cells (109)

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Furthermore, these nanocarriers are capable of depleting GSH levels in the tumor microenvironment to augment stress on cells and induce cell death pathways, including ferroptosis, making cancer cells sensitive to treatment Fig