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Results FAP-specific activation of promellitin-modified liposomes (PRL) PRL and various other liposome formulations, including plain PEGylated liposomes (PL), maleimide-activated PEGylated liposome (ML), scrambled cys-promelittin peptide-tagged liposomes (SCL) and promelittin-mimicking fluorescence-quenched peptide-tagged liposomes (FQL) are schematically depicted in Fig

violin plots show median and quartiles

Conclusions Although challenges associated with some of these compounds remain, important advances have been made in the development of safer and more effective drugs that could actually represent a breakthrough for fatal degenerative diseases such as ALS

doi: 10.1017/S0007114515001099 42 HouYCWuJMChenKYChenPDLeiCSYehSLet al