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In Drosophila , this approach facilitates the creation of LOF or GOF mutant alleles, providing a powerful tool for dissecting gene functions

Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells

The researchers successfully constructed the cBEST gene editing system by knocking out three restriction endonuclease genes in Bifidobacterium [100]

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