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Some suggest collagen peptides are better absorbed on an empty stomach, such as first thing in the morning but the clinical evidence isnt there yet

Here is a brief overview of the process: Methione is methylated into S-Adenosylmethionine (SAMe) SAMe is converted into S-Adenosylhomocysteine (SAH) SAH finally converts to homocysteine Homocysteine gets converted into Cystathionine by the enzyme Cystathionine-Beta-Synthase (CBS) Finally Cystathionine is further converted into Cysteine via the enzyme Cystathionin-Gamma-Lyase (CGL) The next stage involves the transformation of cysteine into sulfite via several steps