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Mitochondrial double-stranded RNA triggers antiviral signalling in humans

Zhu M, Zhu M, Wu X, Xu M, Fan K, Wang J, Zhang L, Yin M, Wu J, Zhu Z, Yang G

In splenocytes from WT mice, pretreatment of MS (0.4 mM, Gpx inhibitor) for 48 h inhibited Con A-induced cytokines such as IL-2, IFN- and TNF- (Figure 7a)