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2276-C ALLO-LCA, A BILE ACID DERIVATIVE WITH DUAL ACTIVITY ON GPBAR1 AND RORT, ALLEVIATES NASH-INDUCED LIVER FIBROSIS Michele Biagioli 1 , Cristina Di Giorgio 1 , Martina Bordoni 1 , Silvia Marchian 1 , Carmen Massa 1 , Rachele Bellini 1 , Ginevra Urbani 1 , Eleonora Distrutti 2 , Angela Zampella 3 and Stefano Fiorucci 1 , (1)University of Perugia, (2)Azienda Ospedaliera Di Perugia, (3)University of Naples, Federico II Background: NAFLD is due to the pathological accumulation of lipids in hepatocytes