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doi: 10.1007/s11306-015-0772-0 255 LaiZ-WHanczkoRBonillaECazaTNClairBBartosAet al

Once reconstituted in solvent, peptide stability drops significantly and refrigerated storage with a limited usable window is standard guidance specific timelines depend on the reconstitution protocol used

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Metreleptin Metreleptin (MYALEPT) is an injectable human recombinant leptin analogue approved in Japan for metabolic disorders including lipodystrophy and in USA as first-line treatment for non-HIV related forms of generalized lipodystrophy (leptin deficiency, congenital/acquired lipodystrophy) (22)