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Additionally, in the docked complex, Arg 44 and the 2-methoxy phenol ring revealed a hydrogen-bonding interaction, while a pi-anion interaction was observed between the 2-methoxy phenol ring and Asp 41 (Fig

Of note, IL-11 has no cysteines but its intracellular precursor has two 24 , so it is interesting that it was only identified intracellularly and not in the secretome