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[304] In December 2022, the FDA amended the authorization for the bivalent booster to be used as the third dose in people aged six months through four years of age

This G6PD-dependent production of NADPH is then used for biosynthesis of effector molecules ( Figure 1A-3 ), as well as ROS/RNS production (via NOX, iNOS) needed for phagocytosis and the oxidative burst ( Figure 1A-2 )