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Description

These interactions may influence drug efficacy or increase the risk of adverse effects

It helps design precision protocols tailored to your biology

d , Representative images (scale bar, 10 m) and statistical analysis of intracellular Fe 2+ levels in MC38 NC or NCOA4 KO cells treated with vehicle or KYN for 16 h

As consequence, the increased cellular l-2HG concentrations lead to inhibition of the electron transport and glycolysis compensating the effects of mitochondrial reductive stress induced by hypoxia (Oldham et al., 2015)