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The genetic variability in the or gene families was also suggested to alter risk of cancer either as a result of decreased inactivation of hormones such as estrogens or due to reduced detoxification of environmental carcinogens and their reactive metabolites (Guillemette, 2003)

Its presence in various brain areas underscores its significance in neurobiology and neuromodulation, making it a subject of interest in research exploring its potential therapeutic applications [2]

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