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the absence of duplicate colonies on the latter indicated the successful curing from the pKD46 plasmid

doi: 10.1111/j.1699-0463.1960.tb04748.x 149 KadryH.NooraniB.CuculloL

By using optical markers such as reactive oxygen species (ROS) and senescence-associated -galactosidase (SA--gal), they correlated metabolite signatures, especially related to NAD + metabolism and glutathione homeostasis, with distinct cellular aging states (Wang Z