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All efforts were made to minimize animal suffering and the number of animals used

48 The effective free radical scavenging effect is also shown by Origanum campactumi , Curcuma zedoaria Rosc, Eucalyptus camaldulensis and Phoenix dactylifera

Through the integration of redox biology, spatial-omics, and intelligent nanotechnology, personalized ROS modulation may transform the TME from an immunosuppressive barrier into a redox-calibrated ecosystem optimized for durable antitumor immunity

Nevertheless, although a specific action of homocysteine seems to occur at low concentrations, experimental trials have been conducted only with homocysteine administration, which would reflect a severe hyperhomocysteinemia rather than a more physiologic moderate elevation of circulating homocysteine, and clinical observations have only come from homocystinuric patients with severe hyperhomocysteinemia