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Despite some evidence suggesting that pelleted formulations of cuprizone can be less effective 27,28 , the use of cuprizone in a pelleted form is growing in popularity, with many research groups successfully utilising the pelleted form at chronic timepoints 29,30,31,32,33,34,35,36

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Mills EL, Ryan DG, Prag HA et al (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

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