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Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW

The increasing geometric complexity of the suture patterns in older human lenses results in lenses with better optical properties than in species that maintain a simple Y suture pattern throughout life

However, it should be noted that GSH at high concentrations (e.g., 30 mM) induces morphological changes in HFF-1 cells (Supplementary Figure S1E)

Moreover, PLC and I B phosphorylation was increased by Con A administration in the spleen of WT mice, whereas those phosphorylation did not increase in the spleen of Gpx1 KO mice with Con A administration (Figure 5c)