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Description

DJ-1 plays roles an antioxidant and oxidative stress sensor, contributing to mitochondrial homeostasis

For example, arachidonate 5-lipoxygenase (ALOX5) preferentially oxidizes the PUFA arachidonic acid at carbon-5, resulting in the formation of 5- hydroperoxyeicosatetraenoic acid (5-HPETE) (30)