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Based on another study using kainate-induced rat models, PTGS2 expression was elevated in the CA3, cortex, and dentate gyrus regions 1824 h after seizures

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Nekkab N, Lana R, Lacerda M, Obadia T, Siqueira A, Monteiro W, et al

Larger doses up to 600800 milligrams per day are sometimes used in patients with diabetes or cognitive disorders but not recommended for the general public