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Pro-oxidants in the brain regions were measured by direct determination of MDA peroxidation markers and nitric oxide (NO) concentration

Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans

In the pathology of OA, cellular iron overload can increase localized inflammatory mediators, contributing to OA development ( 2.2 Lipid peroxidation A disruption of cell membrane integrity, which can lead to cell death, represents one potential mechanism through which ferroptosis occurs