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Interestingly, various reports, including a study aimed at developing new insulin analogues thermally more stable and with more physiological profiles than human insulin provided evidence for the possibility to develop IR-A/IGF-1R targeting agents with higher specificity (66)

Watanabe M, Nishino H, Sameshima Y, Ota A, Nakamura S, Hibi T

Abbreviations References 1 AldridgeB

Such an agent must not only possess anti-inflammatory and anti-fibrotic properties but also protect the bladder from oxidative stress damage caused by ischemia-reperfusion injury during the early stages of disease onset, which is a critical requirement